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The Journal of Internal Korean Medicine > Volume 27(3); 2006 > Article
The Journal of Internal Korean Medicine 2006;27(3): 579-588.
항암제로 유발된 백혈구감소증 회복에 미치는 황기의 효과
한인선1, 김병우2
1유민한방병원 내과
2상지대학교 한의과대학 내과학교실
The Effects of Astragali Radix on Cyclophosphamide-induced Leukocytopenia
In-sun Han1, Byoung-woo Kim2
1Department of Internal Medicine
2Oriental Hospital of Sangji University, Wonju, Korea
Correspondence  In-sun Han ,Tel: 032-553-8888, Fax: 032-553-8419, Email: top7524@naver.com
  Published online: September 30, 2006.
ABSTRACT
Objective :
This study was performed to investigate the effect of Astragali Radix on leukocytopenia anaphysis with carcinostatic substance elicitation.

Methods :
We observe if there were differences in a general tendency by EAR (AR extracts) capacity in the Astragali Radix treated group and the cyclophosphamide treated group, a general tendency of recovery from leukocytopenia over time and checked for liver and kidney toxicity.

Results:
In cyclophosphamide treated with EAR 1000mg/kg group, the recovery rate of leukocytopenia increased and there were no differences in liver and kidney functions.

Conclusions:
Astragali Radix was effective and safe in increasing rate of leukocytopenia anaphysis with carcinostatic substance elicitation and indicated possibility for clinically adaptation.
Key words: Cyclophosphamide, Leukocytopenia, Astragali Radix, Toxicity
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