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The Journal of Internal Korean Medicine > Volume 27(3); 2006 > Article
The Journal of Internal Korean Medicine 2006;27(3): 706-714.
Homocysteine과 血中 脂質濃度와의 相關性 硏究
박재현1, 황우준2, 조남근1, 김성철1, 고영철3
1원광대학교 대학원 한의학과
2원광대학교 한의학전문대학원
3삼세한방병원 내과
A Study on Correlation between Homocysteine and Serum Lipids
Jae-Hyun Park1, Woo-Jun Hwang2, Nam-Geun Cho1, Sung-Chul Kim1, Young-Chul Ko3
1Department of Oriental Medicine School of Wonkwang University
2Department of Oriental Medicine Graduate School of Wonkwang University
3Department of Internal medicine, SamSe Oriental Medical Hospital
Correspondence  Young-Chul Ko ,Tel: (051)580-6907, Email: ubong@hanmail.net
  Published online: September 30, 2006.
ABSTRACT
Object:
This study was carried out to investigate the correlation between homocysteine and serum lipids which are known risk factors of stroke.

Methods :
The subjects were a total of 60 patients divided into a control group (n=30) and a sample group (n=30). The control group was normal homocysteine level without clinical symptoms, and the sample group was high homocysteine level with headache, dizziness, hypertension and so on, clinical symptoms. Each group was measured and compared for serum homocysteine, total cholesterol, triglyceride(TG), low density lipoprotein(LDL), and high density lipoprotein(HDL).

Results:
Total cholesterol, TG, and LDL were significantly increased and HDL was significantly decreased in the sample group, which was a high homocysteine level group compared with the control group, which was a normal homocysteine level group.

Conclusion:
In these results, it was suggested that increase of homocysteine leads to increase of serum total cholesterol, TG, LDL, but causes decrease of HDL. It seemed that risk of stroke is more at high homocysteine level than normal.
Key words: Homocysteine, Serum lipids, Stroke
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