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The Journal of Internal Korean Medicine > Volume 29(4); 2008 > Article
Original Article
The Journal of Internal Korean Medicine 2008;29(4): 904-912.
소화불량을 主訴로 내원한 환자에서 呑酸증상 유무와 심박변이도와의 상관성 연구
임인환, 정승환, 엄은진, 이범준, 나병조
강남경희한방병원 내과학교실
Study on the Correlation between Swallowing Acid Symptom and Heart Rate Variability in Dyspepsia Patients
In-hwan Im, Seung-hwan Jeong, Eun-jin Um, Beom-jun Lee, Byong-jo Na
Department of Internal Medicine, Kang-Nam Korean Hospital, College of Oriental Medicine Kyung-Hee University, Seoul, Korea
Correspondence  Beom-jun Lee ,Tel: 02-3457-9006, Fax: 02-3457-9069, Email: franchisjun@naver.com
  Published online: December 30, 2008.
ABSTRACT
Objectives:
The objective of this study was to investigate the correlation between swallowing acid symptom and autonomic nerve system in dyspepsia patients.

Methods :
The test for heart rate variability (HRV) was done to 50 dyspepsia patients at the Department of Internal Medicine, Kang-Nam Kyung-Hee Korean Hospital. 21 among 50 patients had swallowing acid symptom and 29 didn't. We checked HRV and compared HRV index between the two groups. We also divided the patients into functional dyspepsia and organic dyspepsia groups, and then checked HRV respectively.

Results were as follows :
1. In dyspepsia patients with swallowing acid, LF/HF ratio was higher than the dyspepsia patients without swallowing acid but the result was not statistically significant. 2. TP, LF, VLF, and LF/HF ratio was higher in the functional dyspepsia group than in the organic dyspepsia group. Average age in the organic dyspepsia group was significantly higher than in the other group. Both results showed statistically significant difference. 3. In the functional dyspepsia group, LF/HF ratio was significantly higher in patients with swallowing acid symptom than those without. However, in eructation and nausea symptoms, HRV index was not statistically significant.

Conclusion:
This study shows the ratio of sympathetic and parasympathetic nerve system increased in the swallowing acid patient group compared with the non-swallowing acid patient group in functional dyspepsia patients
Key words: Functional dyspepsia, Swallowing acid, Heart Rate Variability (HRV), Autonomic nerve system
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