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The Journal of Internal Korean Medicine > Volume 33(2); 2012 > Article
The Journal of Internal Korean Medicine 2012;33(2): 222-230.
간질성 방광염 환자 25예에 대한 임상적 고찰
손기정1, 오현조1, 이중곤1, 남승규2, 김철중3, 조충식3
1일중한의원
2대전대학교 산업․광고심리학과
3대전대학교 한의과대학 신계내과학교실
Clinical Study of 25 Interstitial Cystitis Patients
Gi-jeong Son1, Hyeon-jo Oh1, Jung-gon Lee1, Seung-kyu Nam2, Chul-jung Kim3, Chung-sik Cho3
1Iljoong Oriental Medical Center
2Dept. of Industrial and Advertising Psychology Medicine, College of Business Administration, Dae-jeon University
3Dept. of Internal Medicine, College of Oriental Medicine, Dae-jeon University
Correspondence  Chung-sik Cho ,Tel: 041-521-8531, Fax: 041-521-7007, Email: choolo2@chol.com
  Published online: June 30, 2012.
ABSTRACT
Background:
Interstitial cystitis is a disorder of the bladder characterized by urgency and frequency of urination, and pelvic pain. The cause of interstitial cystitis is not clear. Modern medical treatments include behavioral therapy, medication, intravesical infusion therapy, and surgical treatment, but the goal of treatment is based on symptom relief rather than a cure. According to a recent report, in an animal model, oriental medicine treatment, Yukmijihwang-tang improved the symptoms of interstitial cystitis. However, clinical studies and experimental research are lacking.

Objectives:
In this study, We investigated Chuknyojetong-tang, acupuncture, moxibustion and bee venom effect on interstitial cystitis.

Methods :
We targeted 25 patients diagnosed with interstitial cystitis at the university hospital and treated them for more than one month. We used acupuncture, Chuknyojetong-tang, and bee venom. The effects were evaluated using ICSI and ICPI at the begin of treatment and at the end of treatment.

Results:
All of the 25 patients were female, average age was 53.3±13.5 years, and the average month of disease-duration was 69.0±59.8. The duration of treatment was 8.0±5.4 months, and 60% of patients were improved. After treatment, we used correlation coefficient method, multiple regression analysis. ICSI difference increased as treatment period increased. ICPI difference increased as age decreased. Total difference also increased as treatment period increased. These results imply that treatment effect was improved.

Conclusions:
These findings suggest that oriental medicine therapy using Chuknyojetong-tang, acupuncture, moxibustion, and bee venom would be very effective on interstitial cystitis.
Key words: Chuknyojetong-tang (suōniàochútòngtāng), interstitial cystitis, interstitial cystitis symptom index (ICSI), interstitial cystitis problem index (ICPI)
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