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The Journal of Internal Korean Medicine 2008;29(4): 887-903. |
| 암 환자의 한약-양약 상호작용에 대한 고찰 |
| 방선휘, 한성수, 조정효, 이연월, 조종관, 유화승 |
| 대전대학교 둔산한방병원 동서암센터 |
| Study about Herb-Drug Interaction for Cancer Patients |
| Sun-hwi Bang, Sung-su Han, Jung-hyo Cho, Yeon-weol Lee, Chong-kwan Cho, Hwa-seung Yoo |
| East-West Cancer Center, Daejeon University, Daejeon, Rep. of Korea |
| Correspondence |
Hwa-seung Yoo ,Tel: 042-470-9132, Fax: 042-470-9006, Email: altyhs@dju.ac.kr
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Published online: December 30, 2008. |
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| ABSTRACT |
Objectives:
We present some opinions to reduce the risk of herb-drug interactions through scanning “About Herbs” of the Memorial Sloan Kettering Cancer Center Website.
Methods :
We searched the Memorial Sloan Kettering Cancer Center Website of About Herbs and investigated herb-drug interactions.
Results:
There are 237 herbs and 196 drugs on About Herbs. 81.1% of herbs have fewer than 2 interactions listed.; 86.3% of drugs fewer than 3 interactions. Especially, 13 herbs were reported to have interactions with inclusive chemoagents on About Herbs. Only L-theanine has positive interaction with inclusive chemoagents. The others have negative interactions with inclusive chemoagents. 12 single chemoagents were reported to have interactions with some herbs. Especially tamoxifen-black cohosh, methotrexate-glutamin and aldesleukin-HuangChihavepositiveinteractionstoincreasetheeffectsofthechemoagent.
Conclusions:
We should urgently create a risk management system of herb-drug interactions and take note of the risk of herb-drug interactions. We should build up systemic, evidence-based informations on popular herbs used by Korean cancer patients and herb-drug interactions in oncology like About Herbs. |
| Key words:
Herb, Drug, Interactions, Cancer Patients |
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