삼화탕이 중간대뇌동맥 결찰로 유발된 뇌허혈에 미치는 영향 |
김동은1, 정승현1, 박인식2, 신길조1, 이원철1 |
1동국대학교 한의과대학 내과학교실 2동국대학교 한의과대학 해부학교실 |
The Effects of Samwha-tang Extracts on Reversible Forebrain Ischemia Experimentally Induced from the Occlusion of Middle Cerebral Artery |
Dong-Eun Kim1, Sung-Hyun Jeong1, In-Sick Park2, Gil-Cho Shin1, Won-Chul Lee1 |
1Department of Internal Medcine, College of Oriental Medcine, Dongguk University 2Department of Anatomy, College of Oriental Medcine, Dongguk University |
Correspondence |
Dong-Eun Kim ,
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Received: June 11, 2001, Accepted: June 26, 2001, Published online: June 30, 2001. |
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ABSTRACT |
The purpose of this investigation is to evaluate the effects of Samwha-tang Extracts on reversible forebrain ischemia experimentally induced from the occlusion of middle cerebral artery. The volume of cerebral ischemia, the volume of cerebral edema, and the change of pyramidal neuron of the CA1 area in hippocampus through light microscopy were investigated. we obtained the following results. The volume of the control group, which had ischemic damage was 21%, and the volume of the sample group, which had ischemic damage, was 16%. The ratio of the volume of the right/left hemisphere was 117.2 in the control group, and 108.8 in the sample group. Also, the light microscopy revealed that the pyramidal cells of CA1 area in hippocampus had many damages like changes into discontinuous and unsystematic forms. But, in the sample group, the cells were less damaged compared with the control group. |
Key words:
Samwha-tang, brain ischemia |
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