A Case Report for a Toxic Liver Injury Caused by Voluntary Administration
of Smilacis Chinae Radix

Kim, Jin-hee; Cho, Jung-hyo; Son, Chang-gue

The Journal of Internal Korean Medicine > Volume 33(4); 2012 > Article

Case Report

The Journal of Internal Korean Medicine 2012;33(4): 609-614.

청미래덩굴 뿌리 복용으로 발생한 독성간염환자 1예의 치료보고

김진희, 조정효, 손창규

대전대학교 간계내과학 교실

A Case Report for a Toxic Liver Injury Caused by Voluntary Administration of Smilacis Chinae Radix

Jin-hee Kim, Jung-hyo Cho, Chang-gue Son

Dept. of Internal Medicine, College of Oriental Medicine, Dae-Jeon University

Correspondence

Chang-gue Son ,Tel: 042-229-6807, Fax: 042-254-3403, Email: ckson@dju.ac.kr

Published online: December 30, 2012.

ABSTRACT

Drug-induced liver injury (DILI) is a common cause of acute hepatitis. Regarding the risk of DILI from herbal preparations, there are controversial issues such as exaggerated reports straying far from the truth and lack of discrimination between herbal drugs and folk remedies or food supplements. This study reported one case of a patient with DILI caused by Smilacis Chinae Radix and cured in an Oriental hospital. Smilacis Chinae Radix has been used as an anti-inflammatory, anti-microbial, detoxification and anticancer compound, as a folk remedy. This report would provide helpful information for management of DILI by folk remedies or herbal drugs.

Key words: Smilacis Chinae Radix, drug-induced liver injury, herbal plant, Korean medicine