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The Journal of Internal Korean Medicine > Volume 29(2); 2008 > Article
The Journal of Internal Korean Medicine 2008;29(2): 359-374.
다한증 환자의 한의학적 변증특성 및 자율신경계 기능과의 상관관계
이성헌, 김재환, 노영래, 이형구, 정승연, 정승기, 정희재
경희대학교 한의과대학 폐계내과학 교실
Correlation between Oriental Medicine Diagnosis and the Autonomic Nervous System Functions of Hyperhidrosis Patients
Sung-hun Lee, Jae-hwan Kim, Young-lae Roh, Hyung-koo Rhee, Seung-yeon Jeong, Sung-ki Jung, Hee-jae Jung
Division of Allergy, Immune & Respiratory System, Department of Internal Medicine, College of Oriental Medicine, Kyung Hee University
Correspondence  Hee-jae Jung ,Tel: 02-958-9147, Fax: 02-958-9148, Email: hanfish@khmc.or.kr
  Published online: June 30, 2008.
ABSTRACT
Objective :
Hyperhidrosis is a condition characterized by excessive sweating. Some studies suggest that hyperhidrosis is associated with autonomic nervous system dysfunction. Hyperhidrosis is often accompanied by hypersensitivity, tension, irritability, heat flashes, fatigue, etc. This study was designed to evaluate the correlation between Oriental Medicine diagnosis and the autonomic nervous system function in patients with hyperhidrosis using Heart Rate Variability (HRV) analysis.

Methods :
23 palmar and plantar hyperhidrosis patients and 10 systemic hyperhidrosis patients were recruited and evaluated by Oriental Medicine diagnostic questionnaire and HRV analysis. The Oriental Medicine diagnostic questionnaire used a three-dimensional diagnosis that classified patients into Cold or Heat Syndrome, Yin or Yang Syndrome, and Deficiency or Excess Syndrome. Measured indices of HRV used the frequency domain analysis(i.e. TP, VLF, LF, HF and LF/HF ratio). Also, measure indices of HRV adjusted for aging effects were evaluated.

Results:
Cold/Heat Syndrome was not associated with hyperhidrosis prevalence nor the HRV analysis in hyperhidrosis patients. The Yang Syndrome group(78.8%) was more strongly correlated than the Yin Syndrome group(21.2%), and character of Yang was correlated with the adjusted TP and adjusted LF. The LF/HF ratio in the Excess Syndrome group was significantly higher than the LF/HF ratio in the Deficiency Syndrome group.

Conclusion:
Hyperhidrosis was not associated with the Cold/Heat Syndrome, but was found to be closely associated with the Yang Syndrome. The LF/HF ratio was significantly higher in the Excess Syndrome group than in the Deficiency Syndrome group in hyperhidrosis patients.
Key words: Hyperhidrosis, Oriental Medicine Diagnosis, Autonomic Nervous System, Heart Rate Variablilty (HRV)
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