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The Journal of Internal Korean Medicine > Volume 28(1); 2007 > Article
The Journal of Internal Korean Medicine 2007;28(1): 47-67.
急性期 中風患者에 대한 中風前兆症 調査 硏究
정재한, 선종주, 최창민, 김석민, 김창현, 민인규, 정동원, 박성욱, 정우상, 문상관, 박정미, 고창남, 조기호, 김영석, 배형섭
경희대학교 한의과대학 심계내과학교실
Clinical Study about Warning Signs of Patients with Acute Stroke
Jae-han Jung, Jong-joo Sun, Chang-min Choi, Seok-min Kim, Chang-hyun Kim, In-gyu Min, Dong-won Jeong, Sung-uk Park, Woo-sang Jung, Sang-kwan Moon, Jung-mi Park, Chang-nam Ko, Ki-ho Cho, Young-suk Kim, Hyung-sup Bae
Department of Cardiovascular & Neurologic Disease(Stroke center), College of Oriental Medicine, Kyung Hee University
Correspondence  Ki-ho Cho ,Tel: 02-958-9128, Fax: 02-958-9132, Email: piodream@freechal.com
  Published online: March 30, 2007.
ABSTRACT
Objectives:
This study was aimed to investigated the warning signs and its relationship with the other characteristics in acute stroke patients.

Methods :
225 acute stroke patients were recruited at the Department of Cardiovascular and Neurologic Diseases (Stroke Center) of Kyung Hee University Oriental Hospital from October 2005 to September 2006. We evaluated their stroke type with brain MRI, their warning signs, and general characteristics such as age, sex, past history, risk factors, etc.

Results:
225 subjects were included in the final analysis. In the subjects' general characteristics, the most common etiology of stroke was small vessel occlusion. In the assessment of the subjects' warning signs, the frequency of tension felt at the cervical area was highest followed by blepharospasm, sensory dysfunction (one side of numbness, tingling sensation, dead sensation), one side paralysis or weakness, etc. After analyzing etiology, cerebral hemorrhage had more facial spasm sign and hypertension than cerebral infarction. On the other hand, cerebral infarction had more diabetes and sensory dysfunction(one side of numbness, tingling sensation, dead sensation) than cerebral hemorrhage. Among stroke locations, subjects with their brain lesion in the cortex had more warning signs of motor dysfunction such as one side paralysis or weakness. Multiple lesions showed a close relationship with smoking habit and were more common in males than in females. The under 65 years old group were more commonly associated with alcohol consumption, accidental mental stress and blepharospam than the over 65 years old group. In the group of under 65 years old, males more commonly had lesions in occipital lobe, alcohol consumption and smoking habit than females. Otherwise, females more commonly had vision dysfunction and blepharospasm than males. In the group of over 65 years old, males more commonly had cortex lesion than females. On the other hand, females more commonly had accidental mental stress than males.

Conclusions:
We observed various warning signs and their distribution in acute stroke patients. The subjects' brainlesions and their etiology seemed to affect the features of the warning signs. Hypertension, diabetes and hyperlipidemia were also related to etiology of stroke and some habitual problems such as smoking and drinking seemed to reduce the age of stroke ictus. Although a concrete conclusion can hardly be drawn from this study, it reminds physicians of the importance of warning signs which appear among their patients.
Key words: Warning sign, risk factor, stroke
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