Warning: fopen(/home/virtual/jikm/journal/upload/ip_log_2021-12.txt): failed to open stream: Permission denied in /home/virtual/lib/view_data.php on line 73 Warning: fwrite() expects parameter 1 to be resource, boolean given in /home/virtual/lib/view_data.php on line 74 A Case Report on ROS1-positive Recurrent Non-small-cell Lung Cancer Treated with Crizotinib and Korean Medicine
| Home | E-Submission | Sitemap | Editorial Office |  
top_img
The Journal of Internal Korean Medicine > Volume 42(5); 2021 > Article
The Journal of Internal Korean Medicine 2021;42(5): 820-832.
doi: https://doi.org/10.22246/jikm.2021.42.5.820
Crizotinib과 한방치료를 병행하여 호전된 ROS1 양성 재발성 폐암 환자 1례
장권준1,2, 양정민1, 이지윤1, 고은비1, 문향란1, 윤민지1, 조온유1, 정성헌1, 이범준2, 신광순1, 황우석1,2
1장덕한방병원
2경희대학교대학원 임상한의학과 폐계내과학교실
A Case Report on ROS1-positive Recurrent Non-small-cell Lung Cancer Treated with Crizotinib and Korean Medicine
Kwon-jun Jang1,2, Jung-min Yang1, Ji-yoon Lee1, Eun-bi Ko1, Hyang-ran Moon1, Min-ji Yoon1, On-you Jo1, Seong-heon Jeong1, Beom-joon Lee2, Kwang-soon Shin1, Woo-seok Hwang1,2
1Jangdeuk Korean Medicine Hospital
2Division of Allergy, Immune & Respiratory System, Dept. of Internal Medicine, Graduate School, Kyung Hee University
Correspondence  Woo-seok Hwang ,Tel: 1800-1135, Fax: 02-593-2052, Email: pato-@nate.com
Received: September 2, 2021,   Accepted: October 19, 2021,   Published online: October 30, 2021.
ABSTRACT
Objectives:
This study examined the case of a patient with ROS1-positive recurrent non-small-cell lung cancer treated with crizotinib and traditional Korean medicine.

Methods:
The patient was treated with crizotinib from January 20 2021 to May 22 2021, together with Haedogyangpye-tang and Haengso-tang. The tumor size was measured using computed tomography (CT), and adverse events were evaluated according to the National Cancer Institute’s Common Terminology Criteria for Adverse Events (NCI-CTCAE) version 5.0.

Results:
After four months of combined treatment, the sizes of the lymph nodes in the porta hepatis, hepatoduodenal, retrocrural, aortocaval, and para-aortic areas had decreased, and no lymph nodes larger than 1 cm in diameter were observed. The side effects of chemotherapy also improved.

Conclusions:
This case study suggests that traditional Korean medicine may alleviate the side effects of chemotherapy, improve quality of life, and complement chemotherapy itself.
Key words: ROS1, non-small cell lung cancer, crizotinib, traditional Korean medicine
Editorial Office
Dongguk University Ilsan Oriental Hospital
27, Dongguk-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 10326 Korea
TEL: +82-31-961-9046   FAX: +82-31-961-9049   E-mail: jikm.edit@gmail.com
About |  Browse Articles |  Current Issue |  For Authors and Reviewers
Copyright © The Society of Internal Korean Medicine.                 Developed in M2PI      |      Admin Login