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The Journal of Internal Korean Medicine > Volume 24(2); 2003 > Article
The Journal of Internal Korean Medicine 2003;24(2): 358-364.
天花散加味方이 고지방식이에 의한 당뇨병 유발 쥐의 혈청 Glucose농도와 지질구성에 미치는 영향
Effects of Cheunhwasangamibang on serum glucose concentration and lipid composition in high fat diet induced diabetic rat
Byoung Woo Kim
Department of oriental medicine, Sangji university, Wonju, Korea
Correspondence  Byoung Woo Kim ,Tel: 033-732-2111, Fax: 033-732-2124, 
Received: April 22, 2003,   Accepted: June 5, 2003,   Published online: June 30, 2003.
ABSTRACT
Effects of Cheunhwasangamibang on serum glucose and lipid composition were investigated in high fat diet induced diabetic rat. Plasma glucose and free fatty acids concentration showed a high reduction in Cheunhwasangamibang groups compared to those of control group and these values decreased to increasing Cheunhwasangamibang concentration. Plasma β-lipoprotein and triglyceride concentration showed a low values in Cheunhwasangamibang groups, however these values showed no significantly different in 4 ml and 6 ml treatment groups. Total cholesterol concentration showed no significantly different in control group and 2 ml Cheunhwasangamibang group, however these values in 4 ml and 6 ml treatment groups showed a reduction compared to those of control group. Plasma LDL-cholesterol concentration showed a reduction in Cheunhwasangamibang group and HDL-cholesterol showed no significantly different in all treatment groups.
Key words: Cheunhwasangamibang, Glucose, Diabetic rat, lipid composition
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