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The Journal of Internal Korean Medicine > Volume 24(1); 2003 > Article
The Journal of Internal Korean Medicine 2003;24(1): 68-74.
뇌졸중환자에서 한약과 양약의 병용투여가 간장 및 신장에 미치는 영향
The effects of Constant Use of Herbal Medicine with Western Medicine On Liver and Kidney Functions
Sang-Wook Lee1, Sung-Wook Park1, Hyung-Chul Lee1, Chang-Nam Ko1, Sung-Woo Yun1, Ji-Young Han2
1Department of Oriental Internal Medicine, Kangnam Korean Hospital, Kyung Hee University
2Department of Oriental Gynecology, Kangnam Korean Hospital, Kyung Hee University
Correspondence  Sang-Wook Lee ,Tel: 02-3457-9173, Fax: 02-3457-9100, Email: carpediem93@hanafos.com
Received: December 6, 2002,   Accepted: February 19, 2003,   Published online: March 30, 2002.
ABSTRACT
Objectives:
The purpose of this study was to evaluate whether herbal medication may injure the liver function and kidney function. We clinically studied the changes of biochemistry and complete blood cell count in patients who were hospitalized in Korean hospital.

Methods :
The subjects were 160 patients admitted in Kangnam Korean hospital, Kyung Hee, whose mean duration of medication was 70 days(min 30, max 252). All patients had been checked biochemistry and complete blood cell count for 30 days since their hospitalization.

Results:
Aspartate aminotransferase(AST), alanine aminotransferase(ALT), alkaline phosphatase(ALP), blood urea nitrogen(BUN) and Creatinine(Cr) decreased significantly on discharge, compared with the values of admissoin(P<0.05). Total protein significantly elevated on dischrge compared with the values of admisson(P<0.05).

Conclusions:
This study suggests that even though there are few toxic herbal medicines, in general, herbal medications which are prescribed by oriental medicine doctors should be carefully administered not to hurt liver and kidney function.
Key words: Herbal medicine, western medicine, liver, kidney
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