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The Journal of Internal Korean Medicine > Volume 21(5); 2000 > Article
The Journal of Internal Korean Medicine 2000;21(5): 829-837.
보양환오탕이 혈전생성관여인자에 미치는 영향
박선영, 박종형, 한양희, 전찬용, 김동우, 박세기, 이청정혜, 고승희, 고재철, 최유경
경원대학교 내과학교실
The Effects of Boyanghwanotang on the Thrombosis Related Factors
Sun-Young Park, Jong-hyung Park, Yang-hi Han, Chan-yong Jun, Dong-u Kim, Se-gi Park, Chung-jung-hye Lee, Seung-hi Go, Jae-chul Go, You-kyung Choi
Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University
Correspondence  Sun-Young Park ,
  Published online: December 30, 2000.
ABSTRACT
Purpose:
To investigate the inhibitory effect of BHE on platelet aggregation and erythrocyte deformability, we performed following experiments.

Methods :
Concentrated Boyanghwanotang (BHE) was fed to rats for 10days. High dose group was treated with 500ß∂/kg and low dose group with 100ß∂/kg.

Results:
BHE enhanced the blood filtration rate, reduced the platelet aggregability, inhibited granule release from collagen-stimulated platelet, the prostaglandin syn-thesis in platelet and enhanced erythrocyte deformability.

Conclusion:
BHE should inhibit thrombos formation due to platlete hyperaggregabili-ty and reduction of erythrocyte deformabi-lity.
Key words: BHE, thrombos, platelet aggregation, erythrocyte deformability
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