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The Journal of Internal Korean Medicine > Volume 21(5); 2000 > Article
The Journal of Internal Korean Medicine 2000;21(5): 819-827.
혈부축어탕이 혈전생성관여인자에 미치는 영향
김영선, 박종형, 한양희, 전찬용, 김동우, 박세기, 이청정혜, 고승희, 고재철, 최유경
경원대학교 내과학교실
The Effects of Hyulbuchukotang (HCE) on the Thrombosis Related Factors
Young-Sun Kim, Jong-hyung Park, Yang-hi Han, Chan-yong Jun, Dong-u Kim, Se-gi Park, Chung-jung-hye Lee, Seung-hi Go, Jae-chul Go, You-kyung Choi
Department of Internal Medicine, College of Oriental Medicine, Kyung-Won University
Correspondence  Young-Sun Kim ,
  Published online: December 30, 2000.
ABSTRACT
Purpose:
To investigate the inhibitory effect of HCE on platelet aggragation and erythrocyte deformiability, we performed following experiments.

Methods :
Concentrated Hyulbuchukotang (HCE) was fed to rats for 10days. We compare normal group with 500ßΣ/ßΣ-high dose group and 100ßΣ/ßΠ-low dose group.

Results:
HCE enhanced the blood filtration rate, erythrocyte deformiability, reduced the platelet aggreablilty and inhibited granule release from collagen stimulated platelet, the prostaglandin synthesis in platelat.

Conclusion:
HCE should inhibit thrombos formation due to platelet hyperaggraeability and reduction of erythrocyte deformiability.
Key words: HCE, thrombos, platelet aggreability, erythrocyte deformiability
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