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The Journal of Internal Korean Medicine > Volume 23(3); 2002 > Article
The Journal of Internal Korean Medicine 2002;23(3): 355-363.
보중익기탕가 창이자의 폐혈전색전 및 지연형 allergy 반응에 대한 효과
박규택, 강필구, 신우진, 김종환, 김성환, 서수현, 이태희, 이선화, 홍상훈, 박동일
동의대학교 부속한방병원 내과학교실
The Effects of the Bojungikgi-tang added Xanthii Fructus on the Pulmonary Thromboembolism and Delayed Allergy Response
Kyu-Taek Park, Pil-Koo Kang, Woo-Jin Shin, , , Soo-Hyun Seo, Tae-Hi Lee, Sun-Hwa Lee, , Dong-Il Park
Department of Internal Medicine, College of Oriental Medicine, Dongeui University
Correspondence  Dong-Il Park ,Tel: 051-850-8651, Fax: 051-867-5162, Email: dipark@dongeui.ac.kr
Received: July 29, 2002,   Accepted: August 31, 2002,   Published online: September 30, 2002.
ABSTRACT
Objective :
This is an experimental study to research the effects of Bojungikgi-tang added Xanthii Fructus on the pulmonary thromboembolism and delayed allergy response.

Methods :
After healthy rats were devided into each group, we injected sodium arachidonic acid in one group, and ADP(adenosine diphosphate) in the other one afterward, to compare the survival rates for the pulmonary thromboembolism test. For the delayed allergy response test, we injected PC(picryl chloride) to one group and measured the thickness of their ears, and SRBC(sheep red blood cell) allergen to the other and measured their foot edema afterward to compare the rates of allergy response?

Results:
The extract of the Bojungikgitang added Xanthii Fructus revealed significant effect on the pulmonary thromboembolism induced by sodium arachidonate or adenosine diphosphate(ADP). And the extract of the Bojungikgitang added Xanthii Fructus revealed significant effect on delayed type hypersensitivity induced by picryl chloride(PC) or sheep red blood cell(SRBC).

Conclusions:
According to the above results it is suggested that the extract of the Bojungikgitang added Xanthii Fructus revealed significant effect on the delayed type hypersensitivity and effect on the pulmonary thromboembolism.
Key words: Xanthii Fructus(Cangerzi), Thromboembolism, Delayed allergy
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