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The Journal of Internal Korean Medicine 2000;21(4): 591-595. |
| 현삼이 SO2로 손상된 흰쥐의 호흡기 조직에 미치는 영향 |
| 이민우, 전종철, 박동일 |
| 동의대학교 한의과대학 폐계내과학교실 |
| The Effects of Scrophulariae Radix on the Injured Tracheal Tissue Induced SO2 in Rats |
| Min-Woo Lee, Jong-Choul Jeon, Dong-Il Park |
| Dept. of Internal Medicine, College of Oriental Medicine, Dongeui University |
| Correspondence |
Dong-Il Park ,
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Published online: November 30, 2000. |
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| ABSTRACT |
Objective :
This experiment was performed in order to study the effects of Scrophulariae Radix on the injured tracheal tissue induced SO2 in rats.
Methods :
Healthy adult male rats weighting about 250g were divided into 4 groups - the Normal group, the Control group, the group of Scrophulariae Radix administration for 5 days after SO2 gas exposure(Sample I), and the group of Scrophulariae Radix administration for 10 days before and for 5 days after SO2 gas exposure(Sample II).
Results:
In the trachea Control group, the lesion of the ciliated epithelium was severe and the mucus secretion of the respiratory tract was increased significantly. In the trachea of Sample I group, the lesion of the ciliated epithelium and the mucus secretion of the respiratory tract were decreased compared with Control group. In the trachea of Sample II group, the lesion of the ciliated epithelium and the mucus secretion of the respiratory tract were decreased compared with Control and Sample I group.
Conclusions:
According to the above results, Scrophulariae Radix has significant effects on the injuried tracheal tissue caused by SO2 in rats. |
| Key words:
현삼, 기관조직, 이산화황 |
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