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The Journal of Internal Korean Medicine > Volume 37(2); 2016 > Article
The Journal of Internal Korean Medicine 2016;37(2): 361-367.
범불안장애를 호소하는 귀비온담탕 가미방 치험 1례
양승보, 김연진, 이형민, 이현중, 조승연, 박성욱, 박정미, 고창남
경희대학교 한의과대학 순환신경내과
Case Report of Generalized Anxiety Disorder Treated with Guibiondamtang-gami
Seung-bo Yang, Yeon-jin Kim, Hyung-min Lee, Hyun-joong Lee, Seung-yeon Cho, Seong-uk Park, Jung-mi Park, Chang-nam Ko
Dept. of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University
Correspondence  Chang-nam Ko ,Tel: 02-440-7702 , Fax: 02-440-7171, Email: kcn202@khu.ac.kr
Received: March 31, 2016,   Accepted: May 22, 2016,   Published online: May 31, 2016.

This clinical study reports on the effect of traditional Korean medicine on a patient with generalized anxiety disorder.


A patient who suffered from generalized anxiety disorder was treated with herbal medicine (Guibiondamtang-gami), acupuncture, moxibustion, and pharmacopuncture. We assessed the changes of anxiety-related symptoms with the state-trait anxiety inventory (STAI) score, the Beck anxiety inventory (BAI) score, a heart rate variability (HRV) test, and a second derivative of photoplethymogram waveform (SDPTG) test.

After taking Guibiondamtang-gami for 22 days, the patient’s STAI score, BAI score, and LF/HF (low-frequency/high-frequency heart rate variability) ratio decreased, while the differential pulse wave index and stress power in the SDPTG test increased.

This clinical case study has demonstrated that traditional Korean medicine may be an effective option for treating generalized anxiety disorder.
Key words: generalized anxiety disorder, Guibiondamtang-gami, state-trait anxiety inventory, Beck anxiety inventory, heart rate variability
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