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The Journal of Internal Korean Medicine > Volume 37(1); 2016 > Article
The Journal of Internal Korean Medicine 2016;37(1): 77-89.
항암화학요법 유발 말초신경병증 변증평가도구 개발을 위한 기초연구
박지혜1, 정인철2, 이석훈3, 이진선4, 배겨레1, 조종관1, 유화승1
1대전대학교 둔산한방병원 동서암센터
2대전대학교 한의과대학 신경정신과교실
3충남대학교 통계학과
4충남대학교병원 외과
Preliminary Study to Develop an Instrument for Pattern Identification and Evaluation for Chemotherapy-induced Peripheral Neuropathy (CIPN)
Ji-hye Park1, In-chul Jung2, Suk-hoon Lee3, Jin-sun Lee4, Kyeo-re Bae1, Chong-kwan Cho1, Hwa-seung Yoo1
1East West Cancer Center, Dunsan Korean Medicine Hospital of Dae-Jeon University
2Dept. of Oriental Neuropsychiatry, College of Korean Medicine, Dae-Jeon University
3Dept. of Statistics, Chung-Nam National University
4Dept. of Surgery, Chung-Nam National University Hospital
Correspondence  Hwa-seung Yoo ,Tel: 042-470-9132, Fax: 042-470-9006, Email: altyhs@dju.kr
Received: February 19, 2016,   Accepted: March 31, 2016,   Published online: March 31, 2016.
ABSTRACT
Objectives:
The aim of this study was to develop a standard instrument of pattern identification and evaluation for chemotherapy-induced peripheral neuropathy (CIPN).

Methods:
The advisory committee for this study was organized by 12 professors of traditional Korean medicine from the Korean Association of Traditional Oncology. The items and structure of the instrument were designed based on a review of previous publications. We revised the instrument in consultation with the advisory committee and received additional advice via email.

Results:
We divided the symptoms and signs of CIPN into four pattern identifications: wind arthralgia (風痺), cold arthralgia (寒痺), dampness arthralgia (濕痺), and arthralgia of the deficiency type (虛痺). We obtained the mean weights to reflect the standard deviations from each symptom of the four pattern identifications, which were scored on a 5-point scale by the advisor committee. After we obtained the answers to discrimination between variable symptoms (變症) and ordinary symptoms (素症) from the 12 experts, we gained the final weight from the combination of the ratio of pattern identification to the number of total answers of the advisory committee and the mean weight.

Conclusions:
The Instrument on Pattern Identification and Evaluation for CIPN was developed through a discussion between 12 experts. There was a limitation that the validity and reliability of this instrument have not been proven. However, the significance of this study was that it is the first Instrument on Pattern Identification and Evaluation aimed at assessing CIPN in traditional Korean medicine.
Key words: CIPN, instrument of pattern identification, instrument of evaluation, symptoms and signs
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