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The Journal of Internal Korean Medicine > Volume 35(4); 2014 > Article
The Journal of Internal Korean Medicine 2014;35(4): 546-555.
뇌신경질환에 사용된 레이저 및 광선치료에 대한 임상 연구 고찰
이경구1, 신종훈1, 이경진1, 선승호2, 한창호3, 장인수4
1우석대학교 한의학대학 한의학과
2상지대학교 한의학대학 한방내과학교실
3동국대학교 한의학대학 한방내과학교실
4우석대학교 한의학대학 한방내과학교실
Review on Laser or LED Therapy for the Photobiomodulation of Diseases of the Cerebral Nervous System
Kyung-goo Lee1, Jong-hun Shin1, Kyung-jin Lee1, Seung-ho Sun2, Chang-ho Han3, In-soo Jang4
1Dept. of Korean Medicine, College of Korean Medicine, Woo-Suk University
2Dept. of Internal Medicine, College of Korean Medicine, Sang-Ji University
3Dept. of Internal Medicine, College of Korean Medicine, Dong-Guk University
4Dept. of Internal Medicine, College of Korean Medicine, Woo-Suk University
Correspondence  In-soo Jang ,Tel: 063-220-8608, Fax: 063-220-8616, Email: mackayj@naver.com
  Published online: December 30, 2014.
ABSTRACT
Objectives:
Recently, many studies have reported beneficial effects from the application of laser and light-emitting diode (LED) therapy for cerebral nervous disease. Transcranial laser therapy and LED therapy may be an effective method to treat diseases of the cerebral nervous system. This study aims to discuss the possibility of laser and LED therapy for cerebral nervous disease by reviewing literature about its effectiveness.

Methods:
We searched papers using PubMed, Science Direct, CINAHL, KTKP, Oasis and NDSL, using the keywords “Laser therapy, low-level", “Transcranial laser", “Transcranial light emitting diode" and “stroke”, “traumatic brain injury”, “dementia”, “anxiety”, “cognitive”, “emotional effects”, “psychiatric disorder”, “multiple sclerosis”, “Parkinson's disease”. The search range included randomized controlled trials (RCTs) and clinical case series. Reviews and animal experiments were not included. Studies not matched with inclusion criteria were excluded.

Results:
A total 1,119 studies were found. 1,100 were excluded from scanning titles and abstracts and finally 9 articles were selected. Among the 9 articles, 5 were RCTs, one was a controlled study, and the other 3 were case reports. They reported that transcranial laser therapy and LED treatment had beneficial effects from photobiomodulation to the cerebral nervous system. Clinical evaluation factors showed favorable trends.

Conclusions:
Transcranial laser therapy and LED therapy seem to be effective to the cerebral nervous system and they may be a favorable choice for cerebral nervous disease.
Key words: transcranial laser therapy, low level laser therapy, transcranial light emitting therapy, cerebral nervous disease, review
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