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The Journal of Internal Korean Medicine 2008;29(4): 1075-1082. |
| 원산지별 홍삼투여에 따른 백서의 자연살해세포 활성도 변화에 대한 연구 |
| 임주혁, 조인영, 민경윤, 이혜영, 김슬지, 박영주, 류재환, 이범준, 김성욱, 주일우 |
1경희대학교 한의과대학 내과학교실 동서협진실
2경희대학교 강남한방병원 내상성인병센터
3경희대학교 동서의학대학원 |
| Comparative Study of Natural Killer Cell Activity after Red Ginseng Medication on Rat |
| Ju-hyuk Im, In-young Cho, Kyoung-yoon Min, Hae-yong Lee, Seul-ji Kim, Young-ju Park, Jae-hwan Lew, Beom-joon Lee, Sung-wook Kim, Il-woo Joo |
1Department of Oriental Internal Medicine, College of Oriental Medicine, Kyunghee University
2Department of Internal Medicine, Kangnam Korean Hospital, Kyunghee University
3Graduate School of East-West Medical Science, Kyunghee University |
| Correspondence |
Jae-hwan Lew ,Tel: 02-958-9096, Fax: 02-958-9294, Email: intmed@khu.ac.kr
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Published online: December 30, 2008. |
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| ABSTRACT |
Objectives:
The purpose of this experiment is comparing the difference on natural killer cell activity through Korean red ginseng and Chinese red ginseng by 51Cr release assay.
Methods :
Thirty rats were equally divided into a Korean red ginseng group, a Chinese red ginseng group and a control group. Korean and Chinese red ginseng were administrated to the rats at 200mg daily for a weak, while 0.9% normal saline was given to the control. Percent specific lysis (PSL) and lytic units (LU) were calculated from spleen cells by 51Cr release assay.
Results:
Percent specific lysis of the Korean red ginseng group was significantly higher than that of the control in the ratio of 100:1, effector cell:target cell (p<0.05). Percent specific lysis of Korean red ginseng group was also significantly higher than that of the Chinese red ginseng group in the ratio of 25:1, effector cell:target cell (p<0.05). Chinese red ginseng showed no effect on NK cell activity.
Conclusions:
These findings suggest that Korean red ginseng improves immunologic function and shows superior effects than Chinese red ginseng. |
| Key words:
Panax, Natural Killer Cells, Immunologic Cytotoxicity Tests |
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