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The Journal of Internal Korean Medicine > Volume 29(3); 2008 > Article
The Journal of Internal Korean Medicine 2008;29(3): 716-729.
만성기침에 대한 보조제제로써 淸咽트로키 복합투여의 임상적 유효성 평가
노영래1, 최준용2, 이성헌1, 김재환1, 정희재1, 정승기1
1경희대학교 한의과대학 폐계내과학 교실
2한국한의학연구원 의료연구부
Clinical Effects of Chungin-troche As an Adjuctive Medicine with Chronic Cough Patients
Young-lae Roh1, Jun-yong Choi2, Sung-hun Lee1, Jae-hwan Kim1, Hee-jae Jung1, Sung-ki Jung1
1Division of Allergy, Immune & Respiratory System, Department of Internal Medicine, College of Oriental Medicine, Kyung Hee University
2Department of Medical Research, Korea Institute of Oriental Medicine
Correspondence  Sung-ki Jung ,Tel: 02-958-9147, Fax: 02-958-9148, Email: jskes@unitel.co.kr
  Published online: September 30, 2008.
ABSTRACT
Objectives:
We designed this study to evaluate the effectiveness of Chungin-troche(CIT) preparation as an adjunctive medicine to a herbal extract of Chungsangboha-tanggagambang(CSBH).

Methods :
A paralled, comparative study of CSBH+CIT and CSBH was conducted on 42 patients of chronic cough who attended Division of Allergy, Immune & Respiratory System, Department of Internal Medicine, College of Oriental Medicine, Kyung Hee University between December, 2007 and June, 2008. The treatment in each group lasted for two weeks. Patients were asked to fill in the Leicester Cough Questionnaire (LCQ) before and after administration of each treatment legimen.

Results:
42 patients completed the trial and no adverse effects were reported. Both CSBH+CIT group and CSBH group showed statistical significant improvement in total LCQ score after 2 weeks from baseline. Social domain score and total score in patients taking CSBH+CIT showed a statistical significant increase compared to those scores in CSBH patients.

Conclusion:
CSBH+CIT compositive preparation and CSBH separate preparation appeared to have some benefits in the treatment of chronic cough. However, additional CIT preparation to CSBH can improve social domain in LCQ of chronic cough patients.
Key words: Chronic cough, Bronchus disease, Chungsangboha-tanggagambang(CSBH), Chungin-troche(CIT), Leicester Cough Questionnaire(LCQ)
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