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The Journal of Internal Korean Medicine 2008;29(3): 657-665. |
| 足三里 자침이 고혈압환자의 혈압과 내피세포 의존성 혈관확장반응에 미치는 영향 |
| 배형섭1, 신애숙1, 박성욱1, 손일석2, 정우상1, 문상관1, 박정미1, 고창남1, 조기호1, 김영석1 |
1경희대학교 한의과대학 심계내과학교실
2경희대학교 의과대학 내과학교실 |
| Effects of Acupuncture at ST36 on Blood Pressure and Endothelial Dependent Vasodilation in Hypertensive Patients |
| Hyung-sup Bae1, Ae-sook Shin1, Seong-uk Park1, Il-suk Sohn2, Woo-sang Jung1, Sang-kwan Moon1, Jung-mi Park1, Chang-nam Ko1, Ki-ho Cho1, Young-suk Kim1 |
1Department of Cardiovascular & Neurologic Diseases (Stroke Center), College of Oriental Medicine, Kyung-Hee University
2Department of Internal Medicine, College of Medicine, Kyung-Hee University |
| Correspondence |
Seong-uk Park ,Tel: 02-440-6217, Fax: 02-440-6296, Email: happyomd@khu.ac.kr
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Published online: September 30, 2008. |
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| ABSTRACT |
Objectives:
The objective of this study was to assess the effect of acupuncture applied at the ST36 point on blood pressure and endothelial dependent vasodilation in hypertensive patients.
Methods :
24 hypertensive patients were recruited and randomized to a study group (12 subjects) or a control group (12 subjects). Both groups took FMD (endothelial-dependant, flow-mediated dilation) measurement and then acupuncture needles were inserted at ST36 for the study group. In the control group, they took sham acupuncture as a control. FMD was rechecked after 10-min acupuncture treatment. Blood pressure was measured before and after acupuncture treatment.
Results:
FMD increased significantly in the study group after acupuncture (9.5±2.0% to 11.1±2.2%), but not in the control group. In both groups, there were no changes in blood pressure and heart rate.
Conclusions:
Acupuncture on ST36 appears to improve endothelial dysfunction of hypertensive patients and this might result from inducing activation of endothelium-derived nitric oxide. |
| Key words:
Flow-mediated dilation (FMD), Endothelial dysfunction, Acupuncture, ST36, Hypertension |
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