| 雙降湯이 高cholesterol 食餌로 誘發된 高脂血症 白鼠에 미치는 影響 |
| 이재휘, 임승민, 안정조, 조현경, 김윤식, 설인찬, 유호룡 |
| 대전대학교부속한방병원 심계내과학교실 |
| The Effects of Ssanggang-tang(Ssanggang-tang) on Rat with Induced
Hyperlipidemia |
| Jae-hwi Lee, Seung-min Lim, Joung-jo An, Hyun-kyung Jo, Yoon-sik Kim, In-chan Seol, Ho-rhyong Yoo |
| Department of Internal Medicine, College of Oriental Medicine, Daejeon University |
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Published online: June 30, 2008. |
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| ABSTRACT |
Objective :
Ssanggang-tang(SGT) is noted as an effective method to treat hyperlipidemia in China. The main purpose of
this study was analysis of the effects of Ssanggang-tang(SGT) on rats induced with caused hyperlipidemia.
Methods :
We observed 3 experimental groups: normal, control, and SGT. Rats were provided a normal diet in the
normal group, and the other groups were provided a hyperlipidemic diet to induce hyperlipidemia. After 2 weeks, SGT was
treated in the SGT group. For 6 weeks, values related to hyperlipidemia were observed in the 3 experimental groups.
Results:
SGT decreased some values related to hyperlipidemia like total cholesterol, low density lipoprotein
cholesterol(LDL cholesterol), triglyceride, acetocoenzyme A acetyltransferase(ACAT), and 3-hydroxy-3-methylglutaryl coenzyme
A reductase(HMG-CoA reductase). However, it showed no effect on weight change or high density lipoprotein cholesterol(HDL
cholesterol).
Conclusion:
These results suggest that SGT might be effective in treatment and prevention of hyperlipidemia. |
| Key words:
Ssanggang-tang, Hyperlipidemia, Cholesterol. |
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