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The Journal of Internal Korean Medicine > Volume 28(4); 2007 > Article
The Journal of Internal Korean Medicine 2007;28(4): 872-885.
뇌졸중 위험지표로서의 일반혈액검사 소견에 대한 환자 - 대조군 연구
이현의1, 강경원2, 유병찬2, 방옥선2, 백경민1, 설인찬1, 김윤식1
1대전대학교부속한방병원 심계내과학교실
2한국한의학연구원 의료연구부
The Case-Control Study on Complete Blood Count as a Risk Factor of Stroke
Hyon-ui Lee1, Kyung-won Kang2, Byeong-chan Yu2, Ok-sun Bang2, Kyung-min Baek1, In-chan Seol1, Yoon-sik Kim1
1Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University
2Dept. of Medical Research, Korea Institute of Oriental Medicine
Correspondence  Yoon-sik Kim ,Tel: 042-229-6806, Fax: 042-254-3403, Email: yoonsik@dju.ac.kr
  Published online: December 30, 2007.
ABSTRACT
Objective :
Stroke is one of the most common causes of death in Korea. This study was done to evaluate the association of complete blood count (CBC) with the risk of hemorrhagic stroke and ischemic stroke.

Methods :
In 217-case patients with ischemic stroke or hemorrhagic stroke and 146 healthy control subjects without stroke, hypertension, diabetes mellitus, hyperlipidemia, or ischemic heart disease and 160 controls without ischemic stroke or hemorrhagic stroke, we tested and compared white blood cell count (WBC), red blood cell count (RBC), hemoglobin (Hgb), hematocrit (Hct) and platelet. These data were statically analyzed by general linear models and binary logistic regression analysis to get each adjusted odds ratio.

Results:
The level of WBC was significantly higher in all cases. The level of RBC, Hct and Hgb was significantly lower in patients of ischemic stroke. The level of platelet was significantly higher in patients of ischemic stroke.

Conclusion:
These results suggest high WBC may be a risk factor of hemorrhagic stroke and ischemic stroke and low RBC, low Hct, low Hgb and high platelet may be risk factors of ischemic stroke in Koreans.
Key words: stroke, complete blood count(CBC), risk factor, case-control study
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