Clinical Analysis of 89 Patients with Severe Acute Ischemic Stroke from 3rd Intensive
Care Unit(East-West Integrated Intensive Care Uint) of Kyung Hee Medical Center

Heo, Hong; So, Hyung-jin; Im, Ju-hyuk; Cho, In-young; Lee, Hae-yong; Min, Kyoung-yoon; Ryu, Jae-hwan; Lee, Beom-jun

The Journal of Internal Korean Medicine > Volume 28(4); 2007 > Article

Original Article

The Journal of Internal Korean Medicine 2007;28(4): 863-871.

경희의료원 제3 중환자실(동서협진중환자실)에 입원한 89명의 중증 급성기 뇌경색 환자에 대한 임상적 고찰

허홍¹, 소형진¹, 임주혁¹, 조인영¹, 이혜영¹, 민경윤¹, 류재환¹, 이범준²

¹경희대학교 한의과대학 내과학교실
²강남경희한방병원 한방내과

Clinical Analysis of 89 Patients with Severe Acute Ischemic Stroke from 3rd Intensive Care Unit(East-West Integrated Intensive Care Uint) of Kyung Hee Medical Center

Hong Heo¹, Hyung-jin So¹, Ju-hyuk Im¹, In-young Cho¹, Hae-yong Lee¹, Kyoung-yoon Min¹, Jae-hwan Ryu¹, Beom-jun Lee²

¹Dept. of Oriental Internal Medicine, College of Oriental Medicine, Kyunghee University
²Dept. of Oriental Internal Medicine, Kang-Nam Oriental Medicine Hospital

Correspondence

Hong Heo ,Tel: 02-958-9098, Fax: 02-958-9212, Email: omd61@khu.ac.kr

Published online: December 30, 2007.

ABSTRACT

Objects:
To gain better insights of East-west integrated treatment of ischemic stroke. We analyzed 89 patients with severe acute ischemic stroke who were admitted to the East-west integrated intensive care unit.

Methods :
Subjects enrollment was from the East-west integrated intensive care unit of Kyung Hee Medical Center from March 2006 to February 2007. Patients were admitted within 14 days after the onset of ischemic stroke. We assessed the subjects’ general characteristics, risk factors, admitting routes and periods, diagnostic imaging, process of western treatment and Korean traditional treatment, complication and consequence.

Results:
The proportion of males was 50.6%, of females 49.4%, average age was male 66.0±10.3 and female 71.1±10.5. Average length of hospital stays was 19.5 days. Monthly admissions were highest in November and December. The admission route was through emergency room (61.8%) or ward (34.8%). Mean Glasgow coma scale score was 10.0±2.5, average time from symptom of onset to hospital admission was 2.3±2.2 days. Dominant ischemic vascular territory was middle cerebral artery (66.3%). Initial western treatment was argatroban (22.5%), urokinase (28.1%), and heparinization (38.2%). Distribution of Sasang constitution of So-yang to Tae-eum to So-eum was equal to 5.4 to 2.9 to 1.5. Major complications were observed in 40 (42.7%) patients. In hospital mortality was 12.4% (11 deaths), all of them caused by aggravation of neurological deficit and only 3 of them with major complications. There appears to be a significant positive relationship between length of hospital stay and occurrence of complications (P<0.05). After discharge from the ICU, 64 (71.9%) patients were improved, 11 (12.4%) patients had expired, and 14 (15.8%) patients were transferred.

Conclusions:
From this study, we suggest that patients with severe acute ischemic stroke should be treated with East-west integrated therapy for more favorable consequences and decreased mortality.

Key words: Ischemic Stroke, Oriental traditional medicine, Intensive care unit