Clinical Analysis on 106 cases of Henoch-Schönlein Purpura

Han, Dong-ha

The Journal of Internal Korean Medicine > Volume 28(3); 2007 > Article

Original Article

The Journal of Internal Korean Medicine 2007;28(3): 570-585.

알레르기성 자반증 106례에 대한 임상적 고찰: Henoch-Schönlein 자반증을 중심으로

한동하

한동하한의원

Clinical Analysis on 106 cases of Henoch-Schönlein Purpura

Dong-ha Han

Handongha Korean Traditional Medical Clinic

Correspondence

Dong-ha Han ,Tel: 02-537-8875, Fax: 02-537-1275, Email: gamchoo@hanmail.net

Published online: September 30, 2007.

ABSTRACT

A clinical study of 106 cases of Henoch-Schönlein purpura was made. The author analyzed the result of Korean traditional medical therapy. It was observed more frequently in female at the sex ratio of 1:1.3. The most prevalent age group was 4~9 years(56.6%). In seasonal incidence, the cases were frequent during spring(50%), and the main specific history was upper respiratory tract infection(48.1%). The duration of contraction was 420.9±1079.3 days. The adults were more chronic than children(p<0.05). The clinical manifestation showed in the skin(100%), the gastrointestinal tract(62.3%), the joints(64.2%), the kidney(25.3%), genitourinary system(11.3%), headache(6.6%), and scalp edema(4.7%) respectively. The first outbreak of symptoms was showing of skin purpura in 77 cases(72.6%) the highest frequency, and the gastrointestinal tract and joints were 16(15.1%) and 12 cases(11.3%) respectively. Of all patients, 22 cases(20.8%) experienced recurrences and 47 patients(44.3%) experienced hospitalization treatment. In the patients group which were recurrence experiences, the recurrence rate was high with patients(63.2%) who usually enjoyed meats and convenience foods and in patients(84%) who treated URI with chemical drugs(p<0.05). The patients group(68.9%) that took steroids also experienced a relatively high recurrence rate. Out of the patients(68.9%) who took treatment with steroids, 46.6% experienced side effects, in orders moon face(100%), weight gain(47.1%), appetite increase(52.9%), and acne, alopecia(11.8%), etc. There was a statistically significant relationship between the period of taking the steroid and the side effects(p<0.05). As the result of the herbal medicine treatment(treatment period ; 6.7±6.2 weeks, a follow-up survey during 15~24 months), 67 patients(91.8%) among the 73 patients(68.9%) under 18 years old recovered completely but 3 cases(4.5%) recurred. 23 patients(69.7%) among the 33 patients(31.3%) above 19 years recovered completely but 5 cases(21.7%) recurred.

Key words: Henoch-Schönlein purpura, Allergic purpura, hypersensitivity vasculitis