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The Journal of Internal Korean Medicine > Volume 28(2); 2007 > Article
The Journal of Internal Korean Medicine 2007;28(2): 250-261.
TCD를 이용한 정상군과 중풍원인질환군의 혈류측정에 관한 비교연구
허정은1, 김영균2, 권정남2, 신원탁1, 김종득2, 이상희2, 손연희2
1삼세한방병원 한방내과
2동의대학교 한의과대학 심계내과학교실
Case-control Study : Cerebral Blood Flow as Measured by TCD in Patients with Risk Factors for Stroke
Jeong-eun Heo1, Young-kyun Kim2, Jung-nam Kwon2, Won-tak Shin1, Jong-deuk Kim2, Sang-hee Lee2, Yeoun-hui Son2
1Department of Internal Medicine, Hospital of Samse Oriental Medicine
2Department of Internal Medicine, College of Oriental Medicine, Dong-Eui University
Correspondence  Young-kyun Kim ,Tel: 051-850-8650, Fax: 051-853-4036, Email: ykkim@demc.or.kr
  Published online: June 30, 2007.
ABSTRACT
Objectives:
The purpose of this study was to evaluate the blood flow using doppler ultrasound of the MCA, ACA, PCA, BA, ICA in the patients with risk factor for stroke.

Methods :
110 patients with risk factor for stroke were selected who had hypertension, diabetes mellitus, hyperlipidemia, or heart disease, as well as 89 healthy adults who did not have any symptoms of those diseases. To evaluate the blood flow, the Vs and Vm of the MCA, ACA, PCA, BA, and ICA in the two groups were measured.

Result:
In normal healthy adults, subjects showed a decrease in the Vs and Vm; with advancing in age, there was a significant difference in the Vs of MCA, PCA, BA, and ICA. There was a significant difference in the Vm of MCA, PCA, BA, and ICA. In normal healthy adults, females showed high velocities in all examined vessels. There was a significant difference in the Vs of BA. There was a significant difference in the Vm of BA, and ICA. There was a decrease in the Vs, and Vm of all examined vessels of patients with risk factors for stroke in comparison with normal healthy adults. There was no significant difference in the Vs. There was a significant difference in the Vm of MCA, ACA, and PCA. Results were the same between patients aged under 50 and total patients in the Vs and Vm of all examined vessels. There were differences between patients aged over 50 and total patients in the Vs of MCA, PCA, BA and for patients aged over 50; patients with risk factor for stroke who had hypertension, diabetes mellitus, hyperlipidemia, or heart disease had higher Vs than healthy adults.

Conclusions:
There was a significant difference in the blood flow velocity between patients with risk factors for stroke and healthy adults. However, this result was different from results of comparison of TCD findings between patients and healthy individuals by age. Therefore, more detailed studies about aged patients are needed.
Key words: Transcranial Doppler Ultrasonography, Cerebral blood flow velocity, Stroke, Pulsatility
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