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The Journal of Internal Korean Medicine 2006;27(1): 55-71. |
| 加味淸上補下湯 熱水抽出物과 알코올抽出物의 指標物質 및 패턴의 比較分析 |
| 민정기, 정희재, 이형구, 정승기 |
| 경희대학교 한의과대학 폐계내과학 교실, 경희대학교 한의과대학 생리학교실 |
| Comparison and Analysis of Several Main Components between Hot Water Extract and Alcohol Extract of Gamichungsangbohatang. |
| Jung-ki Min, Hee-jae Jung, Hyung-koo Rhee, Sung-ki Jung |
| Division of Respiratory System, Dept. of Internal Medicine, College of Oriental Medicine, Kyung Hee University, Seoul, Korea |
| Correspondence |
Sung-ki Jung ,Tel: 02-958-9147, Fax: 02-958-9148, Email: jskes@unitel.co.kr
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Received: February 15, 2006, Accepted: February 24, 2006, Published online: March 30, 2006. |
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| ABSTRACT |
Objectives:
To find out more pharmacologically efficient way of extraction of herbal dicoction, Gamichungsangbohatang (GMCSBHT).
Methods :
Several main components of GMCSBHT was compared and analysed between hot water extract of GMCSBHT and Alcohol(70% ethanol) extract of GMCSBHT via HPLC method.
Results:
Hot water extract of GMCSBHT showed relatively more component content than ethanol extract of GMCSBHT. Also weighted mean of main components of hot water extraction of GMCSBHT was higher than that of alcohol extract of GMCSBHT. But from chromatographic pattern analysis of matching ratio and similarity ratio showed that these two forms of extracts might have different chemical composition, and 3D PDA plot of alcohol extract of GMCSBHT showed high peaks near UV 190∼220nm which was invisible in hot water extract of GMCSBHT.
Conclusion:
Alcohol extract of GMCSBHT may have some special components which do not exist in hot water extract of GMCSBHT. |
| Key words:
Gamchungsangbohatang, GMCSBHT, extract, main components, HPLC |
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