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The Journal of Internal Korean Medicine > Volume 40(1); 2019 > Article
The Journal of Internal Korean Medicine 2019;40(1): 38-57.
doi: https://doi.org/10.22246/jikm.2019.40.1.38
비알코올성 지방간질환의 利水 약재 포함 한약 치료에 대한 최신 임상 연구 동향 - CAJ 검색을 중심으로
김영광1, 조명재2, 문영호1
1동신대학교 한의과대학 내과학교실
2광주자생한방병원 한방재활의학과
Review of Clinical Research about Herbal Medicine Treatment Containing Diuretic Herbs on Non-Alcoholic Fatty Liver Disease - Research on China Academic Journal
Young-kwang Kim1, Myoung-jae Jo2, Young-ho Moon1
1Dept. of Korean Internal Medicine, College of Korean Medicine, Dong-Shin University
2Dept. of Rehabilitation Medicine of Korean Medicine, Gwangju Jaseng Korean Medicine Hospital
Correspondence  Young-ho Moon ,Tel: 061-280-7902, Fax: 061-280-7788, Email: doc4you@hanmail.net
Received: February 20, 2019,   Accepted: March 29, 2019,   Published online: March 30, 2019.
This study reviewed recent clinical research trends regarding the effects of herbal medicine treatment containing diuretic herbs on nonalcoholic fatty liver disease (NAFLD) in China.

We reviewed clinical studies on NAFLD from the China Academic Journal of the China National Knowledge Infrastructure from January 1, 2016, to September 10, 2018.

Thirty-nine papers from 86 studies were reviewed. The most commonly used herbal prescriptions included Alismatis Rhizoma (澤瀉), Salviae miltiorrhizae Radix (丹蔘), Crataegii Fructus (山査), Polia Sclerotium (茯苓), Bupleuri Radix (柴胡), and Cassiae Semen (決明子). The treatment effective rate, liver function test, serum lipid test, radiological examination, and symptom comparisons were used to analyze the treatments. In 32 of the papers, the effective treatment rate was 76.9%-100%, and the effectiveness in the experimental group was significantly higher than that in the control group (p<0.05). The risk ratio for the treatment effective rate was 1.26. The mean difference of ALT was -13.44 U/L (95% confidential interval, -24.45 U/L, -2.44 U/L, p=0.0166).

Herbal medicine containing diuretic herbs has been demonstrated to be an effective and useful treatment for NAFLD. Clinical studies that are more scientific and systematic should be actively conducted in the future, and the results of the current study could be used as basic data in future clinical studies on herbal medicine treatment for NAFLD.
Key words: herbal medicine treatment, diutretic herbs, traditional Chinese medicine, NAFLD, CAJ
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