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The Journal of Internal Korean Medicine > Volume 24(3); 2003 > Article
The Journal of Internal Korean Medicine 2003;24(3): 597-603.
항암제독탕과 항암제독탕가 적탕의 항암효과에 관한 비교연구
A Comparison Study on the Anti-tumor Effect of Hangamjedoktang and Hangamjedoktang with Aluns japonica Stend
Young-Nam Yim, Chong-Hyeong Park, Yang-Hee Han, Dong-Woo Kim, Chan-Yong Jun, Ui-Sil Hong, Eun-Ki Back, Ji-Wan Han, Ho-Yeon Ko
Department of Internal Medicine, College of Oriental Medicine, Kyungwon University
Correspondence  Dong-Woo Kim ,Tel: 02-425-3456, Fax: 02-425-3560, Email: kidow@hanmail.net
  Published online: September 30, 2003.
ABSTRACT
Objectives:
According to preceding studies, Hangam jedoktang (Kangaizhidu-tang) appeared to be statistically significant against cancer, and therefor to seek a better medication for cancer, Aluns japonica Stend. which seems to be effective against cancer was added to the formula and the efficacy of both with and without was compared.

Methods :
To examine the anti-cancer effect of HJ(Hangamjedoktang) and HJJ (Hangamjedoktang with Aluns japonica Stend.), the proliferation effect on S-180, activity of machrophage and splenocyte, the rate of production of IL-2 in the spleen were examined

Result:
results are such as the following. 1. HJ and HJJ let inhibit viability of tumor cell in vitro. 2. HJ and HJJ increased the ACP(Acid phosphatase) activity of the macrophage of the mouse with S-180 transplanted. 3. HJ and HJJ increased the IL- 2 produced from the T-lymphocyte of the spleen cell of the mouse with S-180 transplanted.

Conclusions:
HJ and HJJ is effective against cancer in ways such as activation of macrophage, T-lymphocyte.
Key words: Hangamjedoktang, Aluns japonica Stend. Anti-tumor Effect, macrophage, T- lymphocyte
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