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The Journal of Internal Korean Medicine > Volume 21(4); 2000 > Article
The Journal of Internal Korean Medicine 2000;21(4): 633-639.
구보음과 가미구보음이 폐혈전색전 및 즉시형 Allergy 반응에 미치는 영향
정광식1, 김경민2, 강병령1, 박동일1
1동의대학교 한의과대학 폐계내과학교실
2동의대학교 한의과대학 심계내과학교실
The Effects of Gubo-eum(Jiubao-yin) and Kamigubo-eum(Jiameijiubao-yin) on the Pulmonary Thromboembolism and the Immediately Type Hypersensitivity
Gwang-Sik Jeong1, Gyoung-Min Kim2, Byoung-Ryoung Gang1, Dong-Il Park1
1Department of 5th Internal Medicine, Collage of Oriental Medicine, Dong-eui University, Pusan, Korea
2Department of 2nd Internal Medicine, Collage of Oriental Medicine, Dong-eui University, Pusan, Korea
Correspondence  Gwang-Sik Jeong ,
  Published online: November 30, 2000.
ABSTRACT
Objective :
Experimental studies were done to research the effects of Gubo-eum(Jiubao-yin) and Kamigubo-eum(Jiameijiubao-yin) on the pulmonary thromboembolism and the immediately type hypersensitivity .

Methods :
For measuring the response about the pulmonary thromboembolism, we investigated a survival rate after the intravenous injection of sodium arachidonate and adenocine diphophate(ADP). For measuring the response about the immediately type hypersensitivity, we did the intravenous injection of histamin and serotonin, and phlebotomized and excoriated skin and investigated the amount of escaped pigment.

Results:
The each solid extract of Gubo-eum(Jiubao-yin) and Kamigubo-eum(Jiameijiubao-yin) revealed significant decrease effect on viscosity of mucin solution. The each solid extract of Gubo-eum(Jiubao-yin) and Kamigubo-eum(Jiameijiubao-yin) revealed significant effect on the pulmonary thromboembolism induced by sodium arachidonate and adenocine diphophate(ADP). The each solid extract of Guboeum( Jiubao-yin) and Kamigubo-eum(Jiameijiubao-yin) revealed significant on vascular permeability responses to intradermal histamine and serotonine.

Conclusions:
The each solid extract of Gubo-eum(Jiubao-yin) and Kamigubo-eum(Jiameijiubao-yin) revealed significant effect on the immediately type hypersensitivity and the pulmonary thromboembolism.
Key words: Gubo-eum(Jiubao-yin), Kamigubo-eum(Jiameijiubao-yin), Pulmonary thromboembolism, Immediately type hypersensitivity
Key words: 구보음, 가미구보음, 폐색전증, 즉시형알러지반응
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