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The Journal of Internal Korean Medicine > Volume 36(4); 2015 > Article
The Journal of Internal Korean Medicine 2015;36(4): 570-581.
2000년 이후 갑상선 기능저하증에 대한 국내 한의학 실험연구 체계적 고찰
이민혜, 최유경
가천대학교부속 길한방병원 한방내과
Systemic Reviews of Domestic Experimental Studies of Herbal Medicines Used for Hypothyroidism since 2000
Min-hye Lee, You-kyung Choi
Dept. of Oriental Internal medicine, Gil Oriental Medical Hospital, Ga-Chon University
Correspondence  You-kyung Choi ,Tel: 032-770-1300, Fax: 032-468-4033, Email: kosmos@gachon.ac.kr
Received: December 13, 2015,   Accepted: December 30, 2015,   Published online: December 31, 2015.
ABSTRACT
Objectives:
The purpose of this study was to investigate the experimental studies which was performed by single or complex herbal medicines on hypothyroidism.

Methods:
I searched the domestic experimental studies about single or complex herbal medicines' effects on hypothyroidism that published since 2000 on 4 Korean databases by keywords, ‘thyroid gland', ‘hypofunction', ‘hypothyroidism'.

Results:
11 single herbal medicines and 9 complex herbal medicines in 20 experimental studies have reported their effectiveness and safetiness in PTU-induced hypothyroidism rats by evaluating the changes of several biochemical and hematological indexes.

Conclusions:
In order to make new and more effective medicines on hypothyroidism, there should be further studies by using combinations of herbal medicines and the differences of their mechanisms.
Key words: hypothyroidism, experimental study, herbal medicine
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