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The Journal of Internal Korean Medicine > Volume 35(1); 2014 > Article
The Journal of Internal Korean Medicine 2014;35(1): 50-58.
뇌졸중 후 우울증과 한열허실 변증의 상관관계
이일석1, 박기언1, 홍해진1, 송인자2, 성강경1, 이상관1
1원광대학교 한의과대학 광주한방병원 심계내과학교실
2광주여자대학교 간호학과
Dept. of Oriental Internal Medicine, Daegu Hanny University, Daegu Oriental Hospital
Il-suk Lee1, Kee-eon Park1, Hae-jin Hong1, In-ja Song2, Kang-keyng Sung1, Sang-kwan Lee1
1Dept. of internal medicine and neuroscience, College of Korean Medicine, Won-Kwang university
2Dept. of Nursing, Gwang-Ju Womens University
Correspondence  Sang-kwan Lee ,Tel: 062-670-6407, Email: sklee@wku.ac.kr
  Published online: March 30, 2014.
ABSTRACT
Objectives:
The aim of this study was to analyze relationship between post-stroke depression (PSD) and cold, heat, deficiency and excess patterns.

Methods :
Twenty-eight PSD patients were recruited from STROKE center and measured with questionnaires for cold, heat, deficiency and excess patternvalues and saliva for cortisol awakening response (CAR). Saliva samples were collected immediately, 15, 30 and 45 min after awakening. In addition, Beck Depression Inventory (BDI) and Hamilton Depression Rating Scale (HDRS) were conducted for PSD severity. We conducted correlation analysis to find the relationship between cold, heat, deficiency and excess patterns and CAR or BDI and HDRS.

Results:
Deficiency and excess patterns werepositively correlated with area under the curve with respect to the increase (AUCi), but not with area under the curve with respect to the global (AUCg), in CAR. Furthermore, it was negatively correlated with BDI and HDRS, while cold and heat patterns were not correlated with CAR, BDI and HDRS.

Conclusions:
In terms of deficiency and excess patterns, the higher the PSD severity, the higher the deficiency and the lower the PSD severity, the higher the excess. However, there was not a significant relationship between PSD and cold and heat patterns.
Key words: Post-stroke depression, cortisol awakening response, deficiency and excess, cold and heat patterns
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