국내에 보고된 한국 한의학의 암치료 임상연구에 대한 계통적 고찰 |
박봉기1, 이종훈1, 조종관1, 신현규2, 엄석기3, 유화승1 |
1대전대학교 둔산한방병원 동서암센터 2한국한의학연구원 한약제제연구부 3경희대학교 동서신의학병원 Mμ 통합암센터 |
Systemic Review of Clinical Studies about Oriental Medical Treatment of Cancer in Korea |
Bong-ky Park1, Jong-hoon Lee1, Chong-kwan Cho1, Hyun-kyu Shin2, Seok-ki Eom3, Hwa-seung Yoo1 |
1East-West Cancer Center, Dunsan Oriental Hospital of Daejeon University 2Department of herbal pharmaceutical development, Korean Institute of Oriental Medicine 3Mμ Integrative Cancer Center, East-West Neo Medical Hospital of Kyunghee University |
Correspondence |
Hwa-seung Yoo ,Tel: 042-470-9132, Fax: 042-470-9006, Email: altyhs@dju.ac.kr
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Published online: December 30, 2008. |
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ABSTRACT |
Objectives: Recently, the number of cancer patients who use complementary and alternative medicine (CAM), including oriental medicine, are increasing. Also, evidence for efficacy and safety of cancer CAM is reported continuously. This study was designed to evaluate the quality of the published papers for clinical studies about oriental medical cancer treatment in Korea.
Methods : We searched for clinical research papers on the websites of the Korean oriental medical society and subsidiary academies, Korean traditional knowledge portal, Koreanstudies information service system (KISS), etc. We used the reference words 'cancer', 'malignant tumor', 'leukemia', 'lymphoma', 'multiple myeloma', 'melanoma', etc. We then chose studies that had been presented between 1991 and 2008 and analyzed them by publication year, design, cancer type, intervention, subject and journal.
Results: There were 86 clinical research papers that were published between 1991 and 2008. The number of clinical studies has increased in a time-dependent manner. Case reports and case series studies account for 78% of total clinical research. Studies of lung cancer account for 17%. Studies of cancer-related symptoms of cancer patients account for 38%. Studies of Hang-Am-Dan account for 33%. Studiespublished inthe journal of theKorean Society of Oriental Internal Medicine account for 35%.
Conclusion: The clinical research papers about oriental medicine are increasing over time, but most of the studies are retrospective case reports or case series. Well-designed and prospective clinical trials would be recommended to provide more reliable evidence. |
Key words:
systemic review, clinical research, oriental medicine, cancer |
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