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The Journal of Internal Korean Medicine 2008;29(4): 950-961. |
TCD를 이용한 고혈압환자군과 정상혈압군의 뇌혈류측정에 관한 비교연구 |
허정은1, 김영균3, 권정남3, 김경민3, 김봉현4, 김민규2, 김재규3, 박선미1 |
1삼세한방병원 내과학교실 2삼세한방병원 재활의학과 3동의대학교 한의과대학 내과학교실 4동의대학교 한의과대학 재활의학과 |
Case-control Study : Cerebral Blood Flow as Measured by Transcranial Doppler
Ultrasonography(TCD) in Hypertensives |
Jeong-eun Heo1, Young-kyun Kim3, Jung-nam Kwon3, Kyoung-min Kim3, Bong-hyun Kim4, Min-kyu Kim2, Jae-kyu Kim3, Sun-mi Park1 |
1Department of Internal Medicine, Hospital of Samse Oriental Medicine 2Department of Oriental Rehabilitation Medicine, Hospital of Samse Oriental Medicine 3Department of Internal Medicine, College of Oriental Medicine, Dong-Eui University 4Department of Oriental Rehabilitation Medicine, College of Oriental Medicine, Dong-Eui University |
Correspondence |
Young-kyun Kim ,Tel: 051-850-8650, Fax: 051-853-4036, Email: ykkim@demc.or.kr
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Published online: December 30, 2008. |
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ABSTRACT |
Objectives: The purpose of this study was to compare cerebral blood flow between hypertensives and normotensives using transcranial doppler ultrasonography (TCD).
Methods : I investigated cerebral blood flow of 72 hypertensives and 127 normotensives. To evaluate the cerebral blood flow, I measured the systolic peak velocity(Vs) and mean flow velocity(Vm) of the middle cerebral artery(MCA), anterior cerebral artery(ACA), posterior cerebral artery(PCA), basilar artery(BA), and internal carotid artery(ICA) in the two groups using TCD.
Result: 1. There was a decrease in the Vs and Vm of all examined vessels of hypertensives in comparison with normotensives. There was a significant difference in the Vs of ACA and Vm of ACA, PCA, ICA. 2. In males, there was a decrease in the Vs of ACA, PCA, ICA and Vm of MCA, ACA, PCA, ICA of hypertensives in comparison with normotensives. However, there was no significant difference in the Vs or Vm of all examined vessels. 3. In females, there was a decrease in the Vs and Vm of all examined vessels of hypertensives in comparison with normotensives. There was a significant difference in the Vs of MCA, ACA and BA and Vm of ACA, PCA and BA. 4. In 30-49 year-olds, there was a decrease in the Vs and Vm of all examined vessels of hypertensives in comparison with normotensives. There was a significant difference in the Vs of ACA and Vm of ACA. 5. In 50-69 year-olds, there was a decrease in the Vs of ACA, PCA, BA, ICA and Vm of all examined vessels of hypertensives in comparison with normotensives. However, there was no significant difference in the Vs or Vm of all examined vessels. 6. In 70-89 yesrs old, there was a decrease in the Vs, Vm of PCA, BA, ICA of hypertensives in comparison with normotensives. But, there was no significant difference in the Vs, Vm of all examined vessels.
Conclusions: There was a significant difference in the cerebral blood flow velocity between hypertensives and normotensives. These results suggest that blood pressure has influence on cerebral blood flow.
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Key words:
Transcranial doppler ultrasonography, Cerebral blood flow velocity, Hypertensives, Pulsatility |
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