| 六味地黃湯이 Alloxan으로 誘發된 생쥐의 糖尿病性 腎症에 미치는 影響 |
| 서수환, 김용성 |
| 동신대학교 한의과대학 내과학교실 |
| The Effect of Yookmijihwang-tang(Yookmijihwang-tang:YJT) on Mice with Diabetic Nephropathy Induced by Alloxan |
| Soo-hwan Seo, Yong-sung Kim |
| Dept. of Internal Medicine, Collage of Oriental Medicine, Dong-Shin University |
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Received: July 27, 2005, Accepted: August 12, 2005, Published online: December 30, 2005. |
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| ABSTRACT |
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This study was done to investigate recovery effects of YJT, which has been used clinicallly in diabetes therapy. Mice were administered Alloxan to induce diabetes. Their body weight and kidney weight changes, BUN, creatinine, glucose, total protein and ALP activity in serum, urinalysis, excretion volume of Na+, K+ in urine were measured. The results were as follows: 1. Increase in body weight and kidney weight and the ratio of kidney to body weight of YJT treated group showed similar results with those of normal group. 2. The BUN, creatinine, ALP activity levels in serum of YJT treated group were similar with those of normal group. 3. The glucose level in serum of YJT treated group was better than that of control group 4. The result of the urinalysis in the group of YJT was almost same as that of control group The above results suggest that YJT partially improves the function of the kidney. |
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